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KMID : 1005220060210040273
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Journal of Embryo Transfer
2006 Volume.21 No. 4 p.273 ~ p.280
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Association between Economic Traits and Candidate Gene Polymorphism in Korean Native Pig and Duroc
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Kim Myung-Jick
Oh Jea-Don
Cho K. H.
Lee J. H.
Lee Seung-Soo
Hong Y. S.
Jeon Gwang-Joo
Lee Hak-Kyo
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Abstract
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MC4R, PRKAG3, FABP3, and ESR have reported as important candidate genes related to some economic traits in pigs. To investigate the association between these genes and economic traits, the analysis of restriction fragment length polymorphism (RFLP) was conducted on 147 individuals (96 Durocs and 86 Korea native pigs; KNP) using single nucleotide polymorphism (SNP). Different genotype frequencies of 4 candidate genes were observed in Duroc and KNP. There were significant associations between MC4R polymorphic site and average daily gain (ADG, p<0.05) and backfat thickness (BF, p<0.05) in the Duroc, ADG (p<0.05) and days to 70 kg (p<0.05) in KNP. PRXAG3 polymorphic site were significantly .elated to BF (p<0.05) in the Duroc, ADG (p<0.05) and days to 70 kg (p<0.05) in the KNP. In FABP3, association with BF (p<0.05) in the Duroc, ADG (p<0.05) and days to 70 kg (p<0.05) in the KNP were found. ESR polymorphic site was not significantly associated to any other traits.
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KEYWORD
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Korean native pig, candidate gene, polymorphism, RFLP, SNP
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